EssayCultural Studies Like it Turn in work on time. Sent me two files, a draft and a final.
Recent studies have challenged that view and suggested that while somatic activity near the DBS electrode may be suppressed, high frequency stimulation increases and regularizes the output from the stimulated nucleus by directly activating axons of local projection neurons.
It now appears that suprathreshold currents spreading into regions comprised of axonal fibers passing near or through the target structure as well as surrounding nuclei may also contribute to the beneficial effects of DBS. Together, the stimulation-induced regularization of neuronal output patterns are thought to prevent transmission of pathologic bursting and oscillatory activity within the basal ganglia thalamocortical network, thereby enabling compensatory mechanisms that facilitate normal movements.
This theory, however, does not entirely explain why therapeutic latencies differ between motor symptoms and why after turning off a DBS system the reemergence of motor symptoms differs among patients. Understanding these processes on a physiological level will be critically important if we are to reach the full potential of DBS as a surgical therapy and will in turn undoubtedly lead us to technological and clinical advancements in the treatment of other neurological disorders.
Critique in Conclusion of Paper — there are two organizational patterns 1 — The first paragraph is summary, second paragraph is critique, third paragraph is recommendations note: Conclusions In summary, during the normal ageing process, animals experience age-related cognitive decline.
Historically, it was thought that primary contributions to the aetiology of this decline were massive cell loss 1 and deterioration of dendritic branching 17, However, we now know that the changes occurring during normal ageing are more subtle and selective than was once believed.
Of the brain regions affected by ageing, the hippocampus and the PFC seem to be particularly vulnerable, but even within and between these regions the impact of ageing on neuronal function can differ. The morphology of neurons in the PFC is more susceptible to age-related change, as these cells show a decrease in dendritic branching in rats 30, 31 and humans 32, There is also evidence of a small but significant decline in cell number in area 8A of monkeys that is correlated with working memory impairments Moreover, so far, there are no reports of multiple single unit recordings in the PFC of awake behaving animals.
More is known about the impact of ageing on hippocampal function. Because more is known about the neurobiology of ageing in this brain region, there are therapeutic approaches on the horizon that might modify hippocampal neurobiology and slow age-related cognitive decline or partially restore mechanisms of plasticity.
Considering that the average lifespan is increasing worldwide, understanding the brain mechanisms that are responsible for age-related cognitive impairment, and finding therapeutic agents that might curb this decline, becomes increasingly important.
The number and order of paragraphs parallels the number and order of main topical sections of the paper.
First, there are a sufficient number of studies in some areas despite claims often heard about the lack of evidence for CAM. Second, research findings for some of the CAM therapies reviewed here have demonstrated consistent beneficial outcomes for patients with arthritis and related diseases.
Specifically, there is moderate support for acupuncture in reducing pain as compared with sham acupuncture and limited support for acupuncture as compared with a wait list for OA of the knee.
However, no claims can be made for the superiority of acupuncture across locations of OA and across comparison groups. Further, only limited support exists for the efficacy of acupuncture for FMS with the caveat that acupuncture may actually exacerbate the pain for some patients with FMS.
At this point, little is known about acupuncture for patients with RA. Homeopathy has been demonstrated to be twice as efficacious as placebo for rheumatic conditions, but the outcome was not specifically pain.
Furthermore, the interventions included both simple and complex homeopathy as well as individualized and standard treatments and may not represent the system of homeopathy as practiced.
More research is needed in this area. Some herbals and nutraceuticals are also beneficial in reducing pain.Apr 23, · To help EDC students look at the structure of an academic essay.
How Do I Present Findings From My Experiment in a Report? What is a Run-on Sentence & How Do I Fix It? How Do I Write an Intro, Conclusion, & Body Paragraph? How Do I Incorporate Quotes?
Provides a specific and debatable thesis statement. Strategies for Writing a Conclusion. stress the importance of the thesis statement, give the essay a sense of completeness, and ; leave a final impression on the reader.
Suggestions. Answer the question "So What?" Show your readers why this paper was important. Show them that your paper was meaningful and useful. Please select the most appropriate type of paper needed. If the type of paper you need is not on the list, leave the default choice "Essay" and specify what you need in the Paper details field.
Studybay is an academic writing service for students: essays, term papers, dissertations and much more! We're trusted and chosen by many students all over the world! Aug 28, · How to Restate a Thesis. A thesis statement serves as your paper's (or speech's) guiding idea, alerting readers to the main points of your paper and the direction it will take.
A thesis restatement, which comes in the paper's conclusion, 59%(60).